Assume the height of the box is x.
5 reams of paper have 5 x 500 = 2500 sheets of paper.
This means that each sheet of paper has a thickness of x/2500.
Two sheets of paper have a thickness of 2 times x/2500.
Simplifying the fraction:
Two sheets of paper have a thickness of 1/1250th of the height of the box.
Assume the height is x = 20 cm, then two sheets are 20/1250 = 0.016 cm thick.