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Name and explain four types of changes in chromosome structure.

User Pharaoh
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Solution:

The four types of chromosomal structural abnormalities can be grouped into the following two groups:

Balanced structural anomalies:

1. Translocations: simple or complex movement of chromosome fragments or whole chromosomes. Chromosome breaks and a part of it is attached to a different chromosome.

2. Inversion: where the chromosomal region is flipped so that it points in the opposite direction. That is, part of a chromosome breaks off at two points and the segment in between turns upside down and then rejoins the same chromosome.

Unbalanced structural anomalies:

3. Duplication: where part of a chromosome is copied. This means that a part of the chromosome is duplicated or has two copies. The result is additional chromosomal material.

4. Deletion: where part of a chromosome is removed. That is, there is DNA loss.