Answer: 54080
Since the first number cannot be 0 or 1, there would be only 8 possible numbers for the first number. For the second number, we can now have all 10 numbers.
The number of different combinations of numbers would then be:
![8*10=80](https://img.qammunity.org/2023/formulas/mathematics/college/kx2jn5q54y75fvpk3yryohtlgcros71ci3.png)
Then, for the first letter, we have 26 possible letters, as well as the second letter. The number of different combinations of letters would then be:
![26*26=676](https://img.qammunity.org/2023/formulas/mathematics/college/xm8w2nf9vp1528dvi6vbxgoiya85pvl9qg.png)
So, for a license plate that has 2 numbers and 2 letters, where the first number cannot be 0 or 1, there would be:
![8*10*26*26=54080](https://img.qammunity.org/2023/formulas/mathematics/college/oud15f144nxwaslmhcu8parlnlqodbvutv.png)