Answer is √40 miles
Step by step
The runner is running east then south, the diagonal would make this a right triangle with legs of 6 and 2, with an unknown hypotenuse or diagonal.
Pythagorean theorem says
a^2 + b^2 = c^2
2^2 + 6^2 = c^2
4 + 36 = c^2
40 = c^2
Take the square root of both sides to get your hypotenuse or diagonal path distance
√40 = c