DNA integrity and replication are very important for cell integrity as well as the organism to which they belong. When we are talking of replication we are referring to the process in which the genome in a cell duplicates, this is for cellular reproduction (mitosis) as well as for the generation of gametes (meiosis), nonetheless in this process tends to happen errors, also known as mutations, said mutations can be neutral or can be detrimental for the organism, hence the importance to maintain genome integrity, for this are the correction mechanisms that the cell possess to correct mutations, such as the case of DNA pol I and DNA pol II.