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The protease from the human immunodeficiency virus (HIV) is a target of the drugs used to treat HIV/AIDS. The protease has a mechanism similar to that of renin, described in Problem 44, except that renin consists of a single protein with two catalytic Asp residues, whereas the HIV protease consists of two identical subunits, each of which contributes an Asp residue. Is this an example of convergent or divergent evolution

User Buzzzzjay
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Final answer:

The HIV protease and renin having a similar mechanism but with different structural arrangements is an example of convergent evolution. Convergent evolution is when different species independently evolve similar traits, such as both enzymes using Asp residues for catalysis.

Step-by-step explanation:

The HIV protease and renin sharing a similar mechanism but with differing structural conformations is an example of convergent evolution. Convergent evolution occurs when different species evolve similar traits independently, often to adapt to similar environments or ecological niches, despite not having a recent common ancestor.

In this case, the HIV protease, which is targeted by protease inhibitors in the treatment of HIV/AIDS, has evolved a mechanism for catalytic activity that is analogous to that of renin, a human enzyme - both using two Asp residues in their active sites.

However, the difference in their quaternary structures, with renin being a single protein and the HIV protease being a dimer with each subunit contributing one Asp residue, signifies that the similarities in their catalytic mechanisms arose independently, hence, via convergent evolution.

User Mgyongyosi
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11 votes

Answer:

ws

Step-by-step explanation:

User Fehguy
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