Explanation:
it is always the same. the slope is (y coordinate change / x coordinate change) when going from one point on the line to another.
the direction itself does not matter, but it is important to use the same direction for the x and the y comparison.
I prefer to go from left to right, so let's go from
(-3, 4) to (2, -4).
x changes by +5 (from -3 to 2).
y changes by -8 (from 4 to -4).
the slope is
-8/+5 = -8/5