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What is the role of arsenate reductase in the bioactivation of inorganic human carcinogen?

User Danish Bansal
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Answer:

It is a toxic metalloid that exists in two major inorganic forms: arsenate and arsenite. Arsenite disrupts enzymatic functions in cells, while arsenate behaves as a phosphate analog and interferes with phosphate uptake and utilization.

Long-term exposure to arsenic from drinking water and food can cause cancer and skin lesions. It has also been associated with cardiovascular disease and diabetes. In utero and early childhood, exposure has been linked to negative impacts on cognitive development and increased deaths in young adults.

User Jigar Patel
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