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Scientists wanted to learn more about Griffith’s experiment. They extracted a mixture of various molecules from the heat-killed bacteria. They found that

transformation
no longer occurred when they treated the mixture with enzymes that destroyed
DNA
. This experiment supports the hypothesis that
RNA
is the genetic material.

User Adrian Adamczyk
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1 Answer

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21 votes

Griffith concluded that the heat-killed bacteria somehow converted live avirulent cells to virulent cells, and he called the component of the dead S-type bacteria the “transforming principle.” Fig. 1.1. Schematic diagram of Griffith's experiment which demonstrates bacterial transformation.

User Spoulson
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