Answer:
The European diseases affected the people of the Western Hemisphere greatly. Outbreaks of various diseases brought by the Europeans to the Americas such as smallpox, influenza, malaria, diphtheria, etc. It killed many of the Native Americans and disrupted their societies. Due to the diseases having been in Europe for a longer time, the people got more immune to them, however, this was the first time the Native Americans were exposed to it.
Due to them not being immune, the mortality rate for a Native American catching a disease was extremely high, much higher than they would have been if it was already introduced. The Native Americans also had very limited health care therefore were not able to be treated as well as the Europeans. Because of this, the diseases affected them for much longer periods of time.