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What type of protein regulates the turning on and off of genes?

User Masterfego
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Answer:

Activator protein binding is thought to cause DNA to loop out, bringing the activator protein into physical proximity with RNA polymerase

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User Ermin Dedovic
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Answer:

Activator protein binding is thought to cause DNA to loop out, bringing the activator protein into physical proximity with RNA polymerase and the other proteins in the complex that promote the initiation of transcription. Different cell types express characteristic sets of transcriptional regulators.