The introduction of factories changed the way goods were being made in the colonies because prices were now cheaper and more items were being made.
Factories made it a lot easier to create goods in bulk at a cheaper price, this caused the North to turn to industrialization. The South was still focused on agriculture, as their main source of income was from growing cash crops on plantations. The South also did not have that big of a population compared to the North, while the North was continuing to grow due to their industrialization.
The growing population and factories in the North made industry jobs more abundant. This made it so more items were being produced at even cheaper prices. The introduction of tariffs, made more Americans buy within their own country. This made American factories and businesses do better so they could keep creating products.