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7 votes
Why do nucleotides need to be activated before DNA synthesis?​

User Tlayton
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1 Answer

24 votes
24 votes
They always need a template. They can only add nucleotides to the 3' end of a DNA strand. They can't start making a DNA chain from scratch, but require a pre-existing chain or short stretch of nucleotides called a primer.
User Ieugen
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