Answer:
The arrival of the Europeans affected the Native Americans because they brought guns, horses, and alcohol. The Native Americans showed the Europeans how to fertilize crops and make farming easier.
The Europeans brought diseases that Native Americans were not naturally immune to due to never being exposed to the sickness like Europeans did, and many Native Americans died. Europeans would (much later) end up stripping Native American children of their culture with Indian boarding schools, remove the Native Americans from their land and move them to different countries to try to make more room for European settlers, and were generally not very nice to the Native Americans.