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What enzyme catalyses the reaction of PRPP transfer to hypoxanthine with
formation of IMP?

User Skytree
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1 Answer

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Answer:

HPRT

Step-by-step explanation:

HPRT catalyzes the salvage reactions of hypoxanthine and guanine with PRPP to form IMP and GMP

The formation of GMP from IMP requires oxidation at C-2 of the purine ring, followed by a glutamine-dependent amidotransferase reaction that replaces the oxygen on C-2 with an amino group to yield 2-amino,6-oxy purine nucleoside monophosphate, or as this compound is commonly known, guanosine monophosphate.

User Bing Lan
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