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What general type of mutation has the greatest effect on the protein produce

What general type of mutation has the greatest effect on the protein produce-example-1

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Answer: The most serious of these mutations will be the insertion of 2 bases. Becasue the genetic code is read in triplets, a 2 base insetion will alter the reading frame of the code causing a frameshift mutation meaning every amino acid after the site of the mutation will be incorrect.

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