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The Spanish families are very numerous; Lima according to the lowest computation, containing sixteen or eighteen thousand whites, Among these are reckoned a third or fourth part of the most distinguished nobility of Peru; ... One of these traces, with undeniable certainty, his descent from the Incas. The name of this family is Ampuero, so called from one of the Spanish commanders at the conquest of this country, who married a Coya, or daughter of the Inca. To this family the kings of Spain have been pleased to grant several distinguishing honors and privileges, as marks of its great quality: and many of the most eminent families in the city have desired intermarriages with it. -Jorge Juan and Antonio de Ulloa, A Voyage to South America (1748).

Required:
Based on the source titled A Voyage to South America and your prior knowledge, what was an impact of colonization in the New World?

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The correct answer to this open question is the following.

Based on the source titled "A Voyage to South America" and my prior knowledge, I can say that the impact of colonization in the New World was that Spanish people married Native South American Indians -in this case, Inca people- and they bred a new race called "Mestizos."

These Mestizos were born from a Spanish father/mother and a Native Indian father/mother.

This also happened in Mesoamerica with the Aztec civilization people and the Spanish conquerors.

This was part of the consequences of the Spanish conquest in Mesoamerica and South America, and the later foundation of New Spain.

Let's not forget that one of the negative consequences of the Spanish presence in America was that they brought many mortal diseases such as chickenpox, malaria, smallpox, cholera, and influenza. These diseases almost wipe out 80% of Native American people.