Question

Which of the following molecules can be used in catabolic reactions to generate the carbon backbones required for gluconeogenesis?

a. glutathione, a short peptide containing glutamate, serine and histidine
b. butyrate, a short chain fatty acid
c. fructose, a monosaccharide
d. starch, a polysaccharide

Answer 1

The correct option is A

Step-by-step explanation:

Some amino acids, called glucogenic amino acids, when catabolized convert there carbon backbones to tricarboxylic acid (TCA) cycle intermediates. These intermediates can be subsequently metabolized into carbon dioxide and water with the release of ATP or the formation of glucose (known as gluconeogenesis.

All amino acids (with the exception of leucine and lysine) are glucogenic and can thus generate the carbon backbones required for gluconeogenesis. Thus, the correct option is a.