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Describe the normal process of osteogenesis for compact and spongy bone using the three different types of bone cells and their functions

User Nobleknight
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21 votes

Final answer:

Osteogenesis involves osteoblasts creating bone matrix, differentiating into osteocytes to maintain bone structure, and osteoclasts resorbing bone tissue. Compact bone, comprised of osteons, is dense and supports weight, while spongy bone, featuring trabeculae, helps distribute weight and contains bone marrow.

Step-by-step explanation:

Osteogenesis in Compact and Spongy Bone

Osteogenesis, or bone development, involves the coordination of three primary types of bone cells: osteoblasts, osteoclasts, and osteocytes. Osteoblasts are crucial for new bone formation. They secrete the bone matrix, which consists of collagen fibers and organic ground substance, primarily hydroxyapatite formed from calcium salts. Once osteoblasts become entrapped in the matrix they've secreted, they differentiate into osteocytes, the mature bone cells that maintain bone tissue. Osteoclasts play a role in bone resorption, breaking down the bone tissue which allows for the release of calcium into the bloodstream and also contributing to the remodeling of bone.

In compact bone, osteocytes reside in lacunae, which are arranged in concentric circles around blood vessels within structures called osteons. This dense arrangement allows compact bone to withstand compressive forces and provides support and protection, as seen in the diaphyses of long bones.

Conversely, in spongy bone, which contains trabeculae, the arrangement of bone cells is looser, creating a network that supports shifts in weight distribution and houses bone marrow. Spongy bone is prevalent in areas like the epiphyses of long bones and within flat bones.

Bone matrix, the osteogenic cell cycle, and the differences in cellular arrangement between compact and spongy bone tissues are all important for the overall structure and function of bones. The continuous balance of formation and resorption maintains skeletal health and mineral homeostasis.

User Cherrytree
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Answer:

Osteoblasts penetrate the disintegrating cartilage and replace it with spongy bone. This forms a primary ossification center. Ossification continues from this center toward the ends of the bones. After spongy bone is formed in the diaphysis, osteoclasts break down the newly formed bone to open up the medullary cavity.

User Maurizio Pozzobon
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