The correct answer is False.
Step-by-step explanation
The Freedmen's Office was a plan established by the United States Congress in 1865 to provide food, shelter, and medical services to millions of former black and poor white slaves in the South after the Civil War. Based on the above, it can be inferred that the main purpose of La Oficina de Libertos was not to end segregation in the south but to provide aid to affected minorities in the south after the war. So the answer is False.