Answer:
The correct answer is - option C. The mutation changes a codon in the coding region of the HBB transcript to a stop codon such that translation terminates earlier than it should.
Step-by-step explanation:
As we know the mutant HBB gene that causes thalassemia disorder in an individual, produces a protein that lacks many amino acids. This gene produces shorter protein than the normal HBB gene.
A nonsense mutation takes place in a gene that alters codons so that a stop codon comes before its normal place and generates a shorter or truncated protein product with missing amino acids.
Thus, the correct answer would be - option C.