Answer:
1. Acetylcholine:
- Muscarinic
- Nicotinic
- Associated with mushroom poison
- Only receptor found in parasympathetic synapses
- Associated with tobacco
2. Norepinephrine:
- alpha-Adrenergic
- beta-Adrenergic
- Utilizes calcium ions as a second messenger
Step-by-step explanation:
Acetylcholine (ACh) is a neurotransmitter that acts in both the central and peripheral nervous systems. Cholinergic receptors are receptors that bind to ACh. Muscarinic receptors are G protein-coupled receptors involved in the parasympathetic nervous system, which play roles in a variety of physiological responses (e.g., ACh binds to muscarinic receptors in the pathophysiology of asthma, leading to an increased mucus secretion). Nicotinic receptors bind to nicotine, while muscarinic receptors bind to muscarin (muscarine is a well-known neurotoxic alkaloid found in certain mushrooms). Nicotine receptors are also called cholinergic receptors since they also respond to ACh. On the other hand, norepinephrine (NE) binds to alpha-adrenergic and beta-adrenergic receptors in different tissues. Both alpha-adrenergic and beta-adrenergic receptors are G-protein coupled receptors. Alpha-adrenergic receptors are involved in the regulation of blood pressure and generating a sympathetic 'fight and flight response'; whereas beta-adrenergic receptors modulate sympathetic responses in the cardiovascular, metabolic, and central nervous systems (NE activates the beta1-receptor). NE can induce Ca2+ release, which is a second messenger that controls a wide variety of cellular processes.