Final answer:
The population of the United States is estimated to be about 60 times larger than the population of Colorado.
Step-by-step explanation:
To find the best estimate of how many times larger the population of the United States is compared to the population of Colorado, we can divide the population of the United States by the population of Colorado.
The population of Colorado is more than 5 x 106 people, which is 5,000,000 people.
The population of the United States is more than 3 x 108 people, which is 300,000,000 people.
Dividing these two numbers, we get:
300,000,000 / 5,000,000 = 60
Therefore, the best estimate is that the population of the United States is about 60 times larger than the population of Colorado.