48.0k views
0 votes
TNF and related cytokines can directly induce apoptosis. Which statement about TNF-mediated induction of apoptosis is true? a) TNF promotes cell proliferation. b) TNF inhibits the immune response. c) TNF-induced apoptosis is a protective mechanism. d) TNF-induced apoptosis can contribute to tissue damage and inflammation.

User Honestann
by
7.7k points

1 Answer

4 votes

Answer:D

Explanation:TNF, or Tumor Necrosis Factor, is a cytokine involved in various biological processes, including inflammation and immune response. When TNF binds to its receptors on the cell surface, it can activate a signaling pathway that leads to apoptosis, which is programmed cell death.

While TNF-induced apoptosis can serve as a protective mechanism by eliminating infected or damaged cells, excessive or dysregulated TNF signaling can result in tissue damage and inflammation. TNF-induced apoptosis can contribute to the destruction of cells and tissues, leading to tissue damage and promoting inflammation.

Therefore, the statement that TNF-induced apoptosis can contribute to tissue damage and inflammation is true.

User Mfralou
by
7.3k points
Welcome to QAmmunity.org, where you can ask questions and receive answers from other members of our community.