Final answer:
The resting membrane potential is established by the distribution of ions across the cell membrane. Leakage channels and membrane permeability have a direct effect on the resting membrane potential. Na+/K+-ATPase membrane pumps play a direct role in maintaining the membrane potential.
Step-by-step explanation:
The resting membrane potential is established by the distribution of ions across the cell membrane. leakage channels, which allow Na+ to slowly move into the cell or K+ to slowly move out, play a role in maintaining the membrane potential. Membrane permeability refers to how easily ions can pass through the cell membrane, and it directly affects the resting membrane potential. If the membrane is more permeable to Na+, the resting membrane potential will be closer to the equilibrium potential for Na+, which is around +60 mV. If the membrane is more permeable to K+, the resting membrane potential will be closer to the equilibrium potential for K+, which is around -90 mV.
Na+/K+-ATPase membrane pumps, also known as sodium-potassium pumps, play a crucial role in maintaining the resting membrane potential. These pumps actively transport three Na+ ions out of the cell and two K+ ions into the cell for every ATP molecule hydrolyzed. This helps to establish and maintain the concentration gradients of Na+ and K+ across the cell membrane. The functions of Na+/K+-ATPase membrane pumps are direct because they actively transport ions across the membrane to maintain the resting membrane potential.