Final answer:
The subject of the sentence 'Margot is Anne's sister and she is sixteen' is 'Margot'. The sentence gives information about her relationship to Anne and her age of sixteen.
Step-by-step explanation:
The statement 'Margot is Anne's sister and she is sixteen' is an example of an English sentence. In this sentence, the subject would be 'Margot', as the sentence is providing information about her. Here, the information given is about her relationship to Anne and her age, which is sixteen.
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