Final answer:
Shingles, herpes simplex virus (HSV), and Lyme disease are infectious diseases that should be considered in patients with regional pain without evidence of disease in local internal organs.
Step-by-step explanation:
When a patient presents with regional pain without evidence of disease in local internal organs, one infectious disease that should be considered is shingles. Shingles is caused by the reactivation of the varicella-zoster virus, which initially causes chickenpox. The virus can lie dormant in the nerve tissue and then reactivate, causing pain and a rash in a specific region of the body.
Other potential infectious diseases that may present with regional pain include herpes simplex virus (HSV) and Lyme disease. HSV can cause pain and blisters in specific areas, while Lyme disease, transmitted through tick bites, can cause joint pain and inflammation.
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