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"Acute noncompressive nucleus pulposus extrusion (ANNPE): part(s) of IVD affected? damage results from? breeds affected? onset? important clinical signs? how is it diagnosed?"

User Simibac
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Final answer:

ANNPE is a veterinary condition affecting the nucleus pulposus part of IVD, commonly in small breeds of dogs like Dachshunds. It presents suddenly with severe pain and neurological deficits such as paralysis. Diagnosis is generally made using clinical signs and MRI scans.

Step-by-step explanation:

Acute noncompressive nucleus pulposus extrusion (ANNPE) is a condition that affects the nucleus pulposus component of the intervertebral disc (IVD). The common damage results from the sudden extrusion of the nucleus pulposus into the spinal canal without any compression on the spinal cord. Usually, it affects small breeds of dogs, particularly the kind breeds towards Dachshunds, French Bulldogs, and Pekingese. This condition has an acute onset, generally affecting dogs suddenly without any prior symptoms. The main clinical signs involve severe neck or back pain and major neurological deficits such as paralysis. Diagnosis commonly involves a combination of clinical signs, MRI scans, and sometimes, cerebrospinal fluid analysis.

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