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Which of the following medications has both anti-inflammatory and bronchodilator effects, improves FEV1, and reduces exacerbations in patients with stage III or IV COPD? *A.* Tiotropium *B.* Breo Ellipta *C.* Anoro Ellipta *D.* Roflumilast *E.* Indacaterol

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Final answer:

Roflumilast is the medication with anti-inflammatory and bronchodilator effects, improving FEV1, and reducing exacerbations in patients with severe stage III or IV COPD.

Step-by-step explanation:

The medication with both anti-inflammatory and bronchodilator effects, which improves forced expiratory volume in one second (FEV1), and reduces exacerbations in patients with COPD stage III or IV, is Roflumilast (option D). This is an oral medication used to treat severe COPD to decrease the number of exacerbations and improve overall lung function. Unlike the others listed, Roflumilast has anti-inflammatory properties and contributes to opening the air passages in the lungs to help breathing.

Learn more about Roflumilast

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