Final answer:
Enzymes' 3-dimensional structure can be altered outside their optimal pH range, affecting their activity. Structural changes can lead to enzyme denaturation and loss of function.
Step-by-step explanation:
When enzymes are exposed to pH levels outside of their optimal range, their 3-dimensional structure can be altered, which can lead to a loss of enzyme activity. The structure of an enzyme is directly related to its function, so any changes in structure can affect its ability to catalyze reactions. Above or below the optimal pH range, the enzyme may denature, causing it to unfold or lose its shape.
Learn more about Enzyme structure