The Indo-European impact on Mesopotamia was relatively limited compared to other regions. Mesopotamia, located in modern-day Iraq and parts of Syria and Iran, was home to ancient civilizations like the Sumerians, Akkadians, Babylonians, and Assyrians.
While Indo-European peoples, such as the Hittites and Mitanni, did come into contact with Mesopotamia through trade and conquest, their influence was primarily seen in peripheral areas, especially in Anatolia (modern-day Turkey) and the northern parts of Mesopotamia.
The most significant Indo-European impact in Mesopotamia was the Hittite Empire's interactions with the Hittite-Luwian-speaking Mitanni Kingdom. These interactions included diplomacy, trade, and cultural exchange.
In essence, Indo-European impact on core Mesopotamia remained limited, as the indigenous civilizations of the region had already established their rich cultures, languages, and institutions long before significant Indo-European migrations and influences reached the area.