Question

How does von Gierke's disease present (5)? a) Hyperglycemia, muscle cramps, myoglobinuria, fatty liver, elevated CK b) Hypoglycemia, muscle weakness, ketosis, elevated liver enzymes, hyperlipidemia c) Hyperglycemia, pancreatitis, elevated blood urea nitrogen, myoglobinemia, hypotension d) Hypoglycemia, muscle cramps, hyperlipidemia, elevated creatinine kinase, fatty liver

Answer 1

Von Gierke's disease, or Glycogen storage disease type I, is characterized by symptoms such as hypoglycemia, muscle weakness, ketosis, elevated liver enzymes, and hyperlipidemia.

Step-by-step explanation:

Von Gierke's disease, also known as Glycogen storage disease type I, is characterized by symptoms that include hypoglycemia (low blood sugar), muscle weakness, ketosis, elevated liver enzymes, and hyperlipidemia (high fat levels in the blood). These symptoms are primarily because of the body's inability to convert glycogen into glucose. This lack of glucose triggers hypoglycemia and forces the body to use fat as an energy source, which then causes ketosis and hyperlipidemia. The elevated liver enzymes indicate that the liver is under stress or damage, a common issue in Von Gierke's disease due to excessive glycogen storage in the liver.

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