Final answer:
Scientists compare cancerous genomes to normal genomes to find mutations and other changes that might explain cancer development and help tailor treatments.
Step-by-step explanation:
When comparing the sequence of a genome with cancer to the sequence of a normal genome, scientists look for differences between them. These differences may include mutations, changes in the number or structure of chromosomes, or alterations in the DNA sequences that structure genes and regulatory elements. By identifying these variations, researchers can better understand the genetic basis of cancer and develop targeted treatments or preventive strategies, contributing to the field of pharmacogenomics.