To find the difference of 22 and six divided by the sum of 5 and 3, we need to follow the order of operations, which is commonly known as PEMDAS (Parentheses, Exponents, Multiplication and Division from left to right, and Addition and Subtraction from left to right).
1. Calculate the sum of 5 and 3: 5 + 3 = 8.
2. Divide 6 by the sum obtained in the previous step: 6 / 8 = 0.75.
3. Find the difference between 22 and the result from step 2: 22 - 0.75 = 21.25.
Therefore, the difference of 22 and six divided by the sum of 5 and 3 is 21.25.