Answer:
Option C, naloxone
Step-by-step explanation:
Naloxone is an antidote medication administered intranasally, intravenously (IV), intramuscularly (IM), or subcutaneously (subcut, subq) in the event that a patient suffers an overdose or toxicity from opioids, both medical and recreational. The patient is often unconscious or extremely sedated due to the central nervous system and respiratory depression caused by opioids. It works by blocking opioid receptors without activating them. In doing so, it does not eliminate the opioid from the patient's circulatory system however. Free opioid is still in their bloodstream so following administration, it is extremely important for these patients to receive emergency medical treatment.
Methadone is an opioid medication itself so it would not be given to reverse an opioid toxicity. However, it is prescribed because of its ability to suppress the withdrawal symptoms of patients who have taken opioids while also decreasing pain as an analgesic.
Clonidine is an antihypertension medication called an alpha-2 agonist. It has an off-label indication for opioid withdrawal, however, it is not an opioid reversal agent.
Lastly, disulfiram is an enzyme inhibitor used to support cessation of alcohol use. It inhibits an enzyme called aldehyde dehydrogenase present in liver and stomach to breakdown alcohol. Without it, the patient experiences unpleasant distress that can range from diaphoresis, nausea, and vomiting to cardiac events. This is not an opioid antidote.