Final answer:
The primary factors leading to the fall of Rome included unstable leadership, high taxes and inflation, and natural disasters. However, the invasions from the Carthaginians did not contribute to Rome's collapse, as these occurred during Rome's rise, not its fall.
Step-by-step explanation:
All of the given factors contributed to the fall of Rome, except for invasions from the Carthaginians. While there were unstable leadership issues from weak rulers, high taxes and inflation, and even natural disasters causing drought, famine, and plague - Rome indeed faced many crises. But by contrast, the major invasions that lead to Rome's collapse were not from the Carthaginians, but from various barbarian tribes like the Huns, Visigoths, and Ostrogoths. The Punic Wars against Carthage were significant, but they actually took place during the rise of Rome.
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