Final answer:
If Mary does not have hemophilia, she must be a carrier of the mutated gene. Since her husband does not have hemophilia, their chances of having a son with hemophilia are 0%. This can be illustrated using a Punnett square.
Step-by-step explanation:
Hemophilia is an X-linked recessive disorder, meaning it is inherited on the X chromosome. Since Mary does not have hemophilia, she must have received a normal X chromosome from her mother. However, since her father has hemophilia, he must have passed on the mutated X chromosome to Mary. When Mary marries a man who does not have hemophilia, he would have a normal X chromosome to pass on to their children. Therefore, the chances of Mary having a son with hemophilia are 0%, as he would need to inherit the mutated X chromosome from both parents.
To illustrate this, let's create a Punnett square:
Mary's Genotype: XhX
Man's Genotype: XNY
Possible Gametes for Mary: Xh
Possible Gametes for Man: XN or Y
The Punnett square would show that all possible offspring would have a normal X chromosome, XN, and therefore, no son can have hemophilia.