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Of the following methods, which can NOT be used to separate a mixture of enantiomers? A fractional distillation (separation based on a difference in boiling points) B chiral resolving agents C chiral column chromatography D All of the above methods can be used to separate enantiomers.

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Final answer:

The method that can NOT be used to separate a mixture of enantiomers is chiral column chromatography.

Step-by-step explanation:

The method that can NOT be used to separate a mixture of enantiomers is C. chiral column chromatography.

Chiral column chromatography is a separation technique that involves using a stationary phase with chiral properties to separate enantiomers. The stationary phase contains a chiral resolving agent, which interacts differently with the enantiomers based on their specific chirality. This allows for the separation of the enantiomers. However, if a mixture of enantiomers is already separated, chiral column chromatography would not be needed, as it is a method used specifically for separating enantiomers.

User Habin
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Final answer:

Chiral resolving agents cannot be used to separate a mixture of enantiomers.

Step-by-step explanation:

Of the given methods, chiral resolving agents cannot be used to separate a mixture of enantiomers. Chiral resolving agents are substances that selectively react with one enantiomer to form a diastereomeric product, which can then be separated from the remaining enantiomer. This method relies on the difference in reactivity between the enantiomers and is not applicable to all cases.

User Charlieface
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