Answer: 25 minutes
From 10:50 PM to 12:00 AM (midnight) is 1 hour and 10 minutes
From 12:00 AM (midnight) to 1:15 PM is 13 hours and 15 minutes
1 hour 10 minutes + 13 hours 15 minutes = 14 hours 25 minutes.
So, the time difference between 10:50 PM and 1:15 PM is 14 hours and 25 minutes.