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Mast cells produce which inflammatory substance in response to allergies?​

Group of answer choices
​fibroblasts
​histamine
​collagen
cartilage

User Urcm
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Mast cells produce histamine in response to allergies. When exposed to allergens, such as pollen, pet dander, or certain foods, mast cells release histamine as part of the body's immune response. Histamine is a potent inflammatory substance that causes blood vessels to dilate and become more permeable, leading to symptoms like redness, swelling and itching. This allergic response is responsible for various allergic reactions, such as hay fever, hives, and asthma. Antihistamines are commonly used to block the effects of histamine and alleviate allergy symptoms.

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User Mozgras
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Answer:

C. Histamine

Mast cells produce the inflammatory substance called histamine in response to allergies. Histamine is released when mast cells are activated during an allergic reaction. It plays a key role in causing the symptoms of allergies, such as itching, redness, swelling, and increased mucus production.

When an allergen enters the body, such as pollen or pet dander, it triggers the immune system to respond. Mast cells, which are a type of immune cell, have receptors on their surface that recognize the allergen. When the allergen binds to these receptors, it causes the mast cells to release histamine.

Histamine then binds to specific receptors on nearby blood vessels, causing them to dilate and become more permeable. This leads to increased blood flow and the leakage of fluid into the surrounding tissues. The increased blood flow can cause redness and warmth, while the leakage of fluid can result in swelling. Histamine also stimulates nerve endings, leading to itching.

In addition to histamine, mast cells can also release other inflammatory substances, such as cytokines and leukotrienes, which further contribute to the allergic response. However, histamine is one of the main mediators of the immediate allergic reaction.

To summarize, mast cells produce histamine in response to allergies. Histamine is responsible for many of the symptoms associated with allergies, such as itching, redness, swelling, and increased mucus production.

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User Schiavuzzi
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