Final answer:
Self-antigens are unique cell-surface glycoproteins coded for by genes of the major histocompatibility complex (MHC). They help the immune system distinguish between self and non-self antigens. Self-antigens play a crucial role in identifying foreign cells, allowing the immune system to attack them while leaving self-cells unharmed.
Step-by-step explanation:
Self-antigens are unique cell-surface glycoproteins that are coded for by genes of the major histocompatibility complex (MHC). They are molecules that the immune system identifies as belonging to the body (self). Antigens, on the other hand, are substances that the immune system recognizes as non-self and triggers a defensive response. Self-antigens play a role in distinguishing between self and non-self antigens, helping the immune system to attack foreign cells while leaving self-cells unharmed.