Question

Which of the following is false about lysosomes?

A) Lysosomes have an acidic interior environment.
B) Early endosomes mature into late endosomes, which mature into endolysosomes, which mature into lysosomes.
C) Lysosomal proteins (lysosome-resident proteins) carry a specific signal that tags/marks them to be transported to the lysosome.
D) Misfolded proteins are sent to lysosomes to be refolded.​

Answer 1

D.

Step-by-step explanation:

D) Misfolded proteins are sent to lysosomes to be refolded.

This statement is false. Lysosomes are organelles in the cell that contain enzymes responsible for breaking down various biomolecules, including proteins, into smaller components. They are involved in the degradation and recycling of cellular waste and damaged organelles. Lysosomes are not responsible for refolding misfolded proteins; instead, misfolded proteins are often targeted for degradation by proteasomes, another cellular organelle responsible for protein quality control and degradation.

Answer 2

D) Misfolded proteins are sent to lysosomes to be refolded.​

Step-by-step explanation:

Misfolded proteins are not sent to lysosomes to be refolded. Instead, they are sent to the endoplasmic reticulum (ER) to be degraded.

The ER has a quality control system that ensures that proteins are folded correctly. If a protein is misfolded, it will be tagged with a signal that directs it to be degraded in the ER.

The other statements are all true about lysosomes.

• Lysosomes have an acidic interior environment, which is necessary for the activity of the hydrolytic enzymes that they contain.
• Early endosomes mature into late endosomes, which mature into endolysosomes, which mature into lysosomes.
• Lysosomal proteins carry a specific signal that tags/marks them to be transported to the lysosome.

So the false about lysosomes is D) Misfolded proteins are sent to lysosomes to be refolded.​

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