Question

Use the original DNA sequence above to write an example of each of the following types of mutations: insertion, substitution, and frameshift.

Answer 1

For example: GGATACCTAGGTAAT

Insertion: GGATGACCTAGGTAAT

a nucleotide that was not present before is inserted into the original sequence

Substitution: CGATACCTAGGTAAT

the first nucleotide was substituted in for another (C for G)

Frameshift (basically a insertion or deletion, we'll try deletion here): GATACCTAGGTAAT

the first nucleotide was deleted, causing the reading frame to be shifted (instead of GGA as the first codon, we have GAT)