Question

What reaction converts acetamide into an amine

Answer 1

Acetamide is a white, water-soluble, crystalline solid, C2H5NO, the amide of acetic acid: used chiefly in organic synthesis.

Amine is any of a class of compounds derived from ammonia by replacement of one or more hydrogen atoms with organic groups.

Acetamide can be converted into an amine by a reduction reaction using a strong reducing agent such as lithium aluminum hydride (LiAlH4) or sodium borohydride (NaBH4). The reaction involves the reduction of the carbonyl group (C=O) in acetamide to a methylene group (CH2), followed by the reduction of the nitrogen atom to an amine group (-NH2). The reaction can be represented as follows:

CH3CONH2 + 4[H] → CH3CH2NH2 + H2O

where [H] represents the reducing agent. The product of this reaction is ethylamine (CH3CH2NH2), which is a primary amine.

Answer 2

Acetamide can be converted to an amine through a reduction reaction. One such reaction is the catalytic hydrogenation of acetamide using hydrogen gas and a catalyst such as palladium on carbon.

Step-by-step explanation:

The reaction proceeds as follows:

CH3CONH2 + 2H2 → CH3CH2NH2 + H2O

In this reaction, the acetamide molecule is reduced by the hydrogen gas in the presence of the palladium catalyst, resulting in the formation of an amine (in this case, ethylamine) and water. The reaction is typically carried out under high pressure and high temperature conditions to ensure complete conversion of the acetamide to the amine.