Answer:
Othello comes to his sleeping wife's bedroom to murder her as punishment for her supposed adultery. He smothers her with a pillow as she asserts her innocence.
Step-by-step explanation:
Throughout the course of the play, we see Iago, someone who Othello believes he can trust, manipulate Othello and sow seeds of doubt of Desdemona's faithfulness. This drives him to rage and jealousy and ultimately leads him to kill Desdemona.