Final answer:
The change in standard reduction potential for the oxidation of malate by NAD+ is calculated as -0.149 V, which is found by subtracting the standard reduction potentials of oxaloacetate/malate from NAD+/NADH.
Step-by-step explanation:
The question pertains to the calculation of the change in standard reduction potential (Δε´ˆ) for the oxidation of malate by NAD+. This is a redox reaction occurring in biochemical pathways, specifically during the citric acid cycle. The Δε´ˆ is calculated by subtracting the standard reduction potential of the agent getting reduced from that of the agent getting oxidized. In this case, the standard reduction potentials are -0.315 V for NAD+/NADH and -0.166 V for oxaloacetate/malate. The change in standard reduction potential for the oxidation of malate by NAD+ can be calculated as follows:
Δε´ˆ = E´ˆ (oxidizing agent) - E´ˆ (reducing agent)
Δε´ˆ = (-0.315 V) - (-0.166 V)
Δε´ˆ = -0.149 V
Therefore, the change in standard reduction potential for the oxidation of malate by NAD+ is -0.149 V.