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What is keratinization and where does it occur?

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Explanation: Keratinization, also termed cornification, is a process of cytodifferentiation which the keratinocytes undergo when proceeding from their post-germinative state (stratum basale) to finally differentiated, hardened cell filled with protein, constituting a structurally and functionally distinct keratin containing surface layer such as stratum corneum.3 Most eukaryotic cells are composed of a cytoskeleton of three components classified based on their diameter and physicochemical properties into microfilaments, intermediate filaments, and microtubules. Microfilaments are the smallest filaments of cytoskeleton with a diameter of 7 nm while microtubules are the largest filamentous structures with a diameter of about 20 nm.4

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