Final answer:
The 'Revolution of 1800' signifies the peaceful transfer of power between political parties in the U.S., which was a first in presidential history and set an important precedent for American democracy.
Step-by-step explanation:
The significance of the “Revolution of 1800” is that it marked the first time in American history that there was a peaceful transfer of power from one political party to another. When Thomas Jefferson, a Democratic-Republican, won the presidency against the incumbent Federalist John Adams, it also symbolized the people's will for a government less focused on central power and more on states' rights and agricultural interests. This transition was remarkable for the time because it showed that political power could change hands without violence, setting a lasting precedent for subsequent presidential elections and the stability of the U.S. political system.