Question

11) Low dopamine levels cause many issues in people suffering from Progressive Supranuclear Palsy. Drugs using the following mechanisms of action could potentially treat this disease except: a) Decrease the reuptake of dopamine b) Inhibit the activity of monoamine oxidase enzymes c) Decrease dopamine's affinity for its receptor d) Stimulate the production of dopamine 12) Potassium ion channels can be opened in response to: a) GABA b) None of these choices c) Glycine d) Muscinaric acetylcholine 13) Binding of acetylcholine to muscarinic receptors opens K+ channels in the heart (generating an IPSP) and closes K+ channels in the smooth muscles of the stomach (generating an EPSP). True False 14) The following statements characterize inhibitory Post Synaptic Potentials except: a) Have positive feedback between repolarization and closing of Na+ gates b) Are the production of summation, which allows the production of graded repolarizations c) None of these choices d) Can be produced by inhibitory neurotransmitters to stimulate the closing of ion channels 15) Membrane effector proteins bind to the following G protein subunit(s): a) Gamma b) Beta c) Beta-gamma complex d) Alpha e) Alpha or beta-gamma complex

Answer 1

11) Decreasing dopamine's affinity for its receptor could potentially treat Progressive Supranuclear Palsy. 12) GABA, glycine, and muscarinic acetylcholine can open potassium ion channels. 13) False. Binding of acetylcholine to muscarinic receptors opens K+ channels in the heart (generating an IPSP) and closes Ca2+ channels in the smooth muscles of the stomach (generating an IPSP). 14) Inhibitory Post Synaptic Potentials (IPSPs) are the production of summation, which allows the production of graded hyperpolarizations. They can be produced by inhibitory neurotransmitters to stimulate the opening of ion channels. 15) Membrane effector proteins bind to the alpha or beta-gamma complex of G protein subunits.