Final answer:
HIV-2 originated from cross-species transmission and is closely related to specific SIVs. HIV's rapid mutation rate illustrates ongoing evolution, with sub-Saharan Africa facing the highest prevalence due to lack of treatment options.
Step-by-step explanation:
Based on the provided information, the true statement about HIV is that it originated from cross-species transmission, with HIV-2 being more closely related to SIV from certain monkey species than to other strains of SIV. HIV is a pandemic affecting millions of people globally, particularly in sub-Saharan Africa.
The Human Immunodeficiency Virus is known for its rapid reproduction rate, which can lead to drug-resistant strains within weeks, illustrating that evolution is an ongoing process. Additionally, the high prevalence of HIV in sub-Saharan Africa is linked to a lack of prevention strategies and treatments.